Table 2.

The binding affinities (ΔG) of optimized all L- and various D-analogs of EQRPR pentapeptide, docked into the target DNA or proteins in kcal/mol.

Target	EQRPR (all L-)	D-EQRPR (all D-)	[DGlu1]-EQRPR	[DGln2]-EQRPR	[DArg3]-EQRPR	[DPro4]-EQRPR	[DArg5]-EQRPR
1BNA-DNA	−6.2	−6.8	−6.4	−6.4	−6.4	−6.1	−6.6
3zdx-integrin	−9.2	−8.5	−8.5	−9.1	−8.0	−8.6	−8.9
4wk0-integrin	−9.6	−10.3	−9.8	−8.7	−9.7	−9.6	−7.4