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. Author manuscript; available in PMC: 2021 Jul 31.
Published in final edited form as: ACS Chem Biol. 2016 Oct 5;11(11):3154–3164. doi: 10.1021/acschembio.6b00730

Figure 4.

Figure 4.

Selected molecules that were hits in the PrOF NMR screen. The Δδ50 was measured by PrOF NMR titration. Percent reduction in signal in the 1H CPMG experiment is indicated by percent drop, and the change in chemical shift upon the addition of ligand at 400 μM is indicated with Δδ.