Figure 1.

Violin Plots showing the distribution of the IgG responses in the sub-groups before, during and after the vaccination with the Sputnik V vaccine. IgG responses against the NP and RBD protein are expressed as S/P ratios on the vertical line of the graph and calculated as described in the Material and Methods section. The participants were divided in 3 sub-groups: seronegative (most likely never infected), seropositive (most likely previously infected) and infected during the study period (breakthrough infections). A positive antibody response or seroconversion, was defined as a titer with an S/P ratio of at least 40%. S/P ratios of < 40% were considered negative.