Table 1.
Demographic and clinical differences between study periods
| Jan 2019–Feb 2020 (n = 537) |
Mar 2020–July 2020 (n = 139) |
p value | |
|---|---|---|---|
| Age, median y (IQR) | 71 (59–82) | 68 (57–77) | 0.05 |
| Female sex, no. (%) | 251 (46.7%) | 62 (44.6%) | 0.65 |
| Race, no. (%) | < 0.01 | ||
| White | 412 (76.7%) | 88 (63.3%) | |
| Black | 88 (16.4%) | 40 (28.8%) | |
| Other/unknown | 37 (6.9%) | 11 (7.9%) | |
| Hispanic ethnicity, no. (%) | 180 (33.5%) | 42 (30.2%) | 0.46 |
| Transfer from outside hospital, no. (%) | 13 (3.0%) | 8 (6.0%) | 0.11 |
| Past medical history, no. (%) | |||
| Hypertension | 417 (77.7%) | 88 (63.3%) | < 0.01 |
| Dyslipidemia | 293 (54.6%) | 74 (53.2%) | 0.78 |
| Diabetes | 186 (34.6%) | 44 (31.7%) | 0.51 |
| Coronary artery disease | 99 (18.4%) | 24 (17.3%) | 0.75 |
| Prior ischemic stroke | 95 (17.7%) | 32 (23.0%) | 0.15 |
| Atrial fibrillation | 93 (17.3%) | 27 (19.2% | 0.56 |
| Tobacco use | 69 (12.9%) | 19 (13.7%) | 0.80 |
| Heart failure | 54 (10.1%) | 20 (14.4%) | 0.15 |
| NIHSS, median (IQR) | 8 (4–16) | 10 (5–17) | 0.16 |
| Proximal large vessel occlusion, no. (%) | 127 (23.7%) | 35 (25.2%) | 0.71 |
| Thrombectomy, no. (%) | 106/127 (83.5%) | 29/35 (82.9%) | 0.93 |
| Door-to-needle, median min. (IQR) | 38 (26–56) | 46 (29–64) | 0.01 |
| sICH | 23 (4.3%) | 6 (4.3%) | 0.99 |
| In-hospital death/discharge to hospice, no. (%) | 48 (8.9%) | 14 (10.1%) | 0.68 |
| Discharge to home/acute rehab, no. (%) | 398 (74.1%) | 97 (69.8%) | 0.30 |
IQR denotes interquartile range, NIHSS National Institutes of Health Stroke Scale, and sICH symptomatic intracerebral hemorrhage within 36 h of thrombolysis