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. 2021 Jul 31;114(1):301–310. doi: 10.1016/j.athoracsur.2021.06.076

Figure 4.

Figure 4

Representative histologic images (hematoxylin and eosin stain) of the alveoli and interstitial regions. (A) COVID-19 survivor (patient 10) with mild, variable interstitial thickening (original magnification ×20). (B) Negative control (patient 5) shows similar interstitial thickening (original magnification ×20). (C) COVID-19 end-stage lung disease (patient 19) exhibits diffuse alveolar damage (original magnification ×10). (D) COVID-19 end-stage lung disease (patient 17) with scattered intra-alveolar macrophages and fibrotic diffuse alveolar damage (original magnification ×10), with interstitial fibrosis supported by positive trichrome staining in the interstitium (inset original magnification ×10). Scale bars (bottom left corner): ∼250 μm.