Supplementary Table 3.
Overall | Q1 | Q2 | Q3 | Q4 | P Values | |
---|---|---|---|---|---|---|
Number of patients | 15,329 | 3114 | 3318 | 3875 | 5022 | |
Age (mean [SD]) | 61.29 (17.71) | 58.69 (18.12) | 60.76 (18.17) | 63.17 (17.38) | 61.81 (17.17) | <.001 |
Race (%) | ||||||
Black | 7643 (49.9) | 1599 (51.3) | 1876 (56.5) | 1783 (46.0) | 2385 (47.5) | .267 |
White | 4101 (26.8) | 958 (30.8) | 995 (30.0) | 1091 (28.2) | 1057 (21.0) | |
Others | 3569 (23.3) | 557 (17.9) | 446 (13.4) | 989 (25.5) | 1577 (31.4) | |
Missing | 16 (0.1) | 0 (0.0) | 1 (0.0) | 12 (0.3) | 3 (0.1) | |
Female sex | 8357 (54.5) | 1598 (51.3) | 1776 (53.5) | 2069 (53.4) | 2914 (58.0) | .28 |
Atrial fibrillation/flutter | 1407 (9.2) | 299 (9.6) | 349 (10.5) | 403 (10.4) | 356 (7.1) | .36 |
Cancer | 2023 (13.2) | 385 (12.4) | 387 (11.7) | 438 (11.3) | 813 (16.2) | .393 |
Cerebrovascular disease (stroke or TIA) | 1989 (13.0) | 307 (9.9) | 367 (11.1) | 348 (9.0) | 967 (19.3) | .437 |
Currently on dialysis | 534 (3.5) | 94 (3.0) | 131 (3.9) | 137 (3.5) | 172 (3.4) | .431 |
Diabetes mellitus | 5400 (35.2) | 1191 (38.2) | 1247 (37.6) | 1420 (36.6) | 1542 (30.7) | .264 |
Dyslipidemia | 5215 (34.0) | 1066 (34.2) | 1257 (7.9) | 1506 (38.9) | 1386 (7.6) | .27 |
Heart failure | 1686 (11.0) | 396 (12.7) | 445 (13.4) | 456 (11.8) | 389 (7.7) | .328 |
Hypertension | 8863 (57.8) | 1890 (60.7) | 2028 (61.1) | 2428 (62.7) | 2517 (50.1) | .228 |
Peripheral artery disease | 414 (2.7) | 104 (3.3) | 85 (2.6) | 136 (3.5) | 89 (1.8) | .412 |
Prior CABG | 420 (2.7) | 81 (2.6) | 118 (3.6) | 106 (2.7) | 115 (2.3) | .424 |
Prior MI | 772 (5.0) | 209 (6.7) | 206 (6.2) | 210 (5.4) | 147 (2.9) | .361 |
Prior PCI | 662 (4.3) | 140 (4.5) | 177 (5.3) | 178 (4.6) | 167 (3.3) | .398 |
Chronic kidney disease | 1942 (12.7) | 448 (14.4) | 429 (12.9) | 538 (13.9) | 527 (10.5) | .338 |
DVT | 475 (3.1) | 104 (3.3) | 122 (3.7) | 128 (3.3) | 121 (2.4) | .413 |
History of smoking | 1013 (6.6) | 235 (7.5) | 312 (9.4) | 206 (5.3) | 260 (5.2) | .359 |
Immune disorders | 703 (4.6) | 129 (4.1) | 151 (4.6) | 242 (6.2) | 181 (3.6) | .416 |
HIV | 167 (1.1) | 22 (0.7) | 34 (1.0) | 50 (1.3) | 61 (1.2) | .476 |
Lupus | 88 (0.6) | 21 (0.7) | 20 (0.6) | 24 (0.6) | 23 (0.5) | .461 |
Rheumatoid | 174 (1.1) | 33 (1.1) | 49 (1.5) | 58 (1.5) | 34 (0.7) | .447 |
Other immune disorder | 285 (1.9) | 60 (1.9) | 53 (1.6) | 120 (3.1) | 52 (1.0) | .437 |
Pulmonary embolism | 301 (2.0) | 80 (2.6) | 77 (2.3) | 74 (1.9) | 70 (1.4) | .417 |
Pulmonary disease | 2703 (17.6) | 574 (18.4) | 630 (19.0) | 767 (19.8) | 732 (14.6) | .322 |
COPD | 1215 (7.9) | 232 (7.5) | 333 (10.0) | 331 (8.5) | 319 (6.4) | .375 |
ILD | 62 (0.4) | 9 (0.3) | 17 (0.5) | 24 (0.6) | 12 (0.2) | .474 |
Asthma | 1373 (9.0) | 290 (9.3) | 286 (8.6) | 409 (10.6) | 388 (7.7) | .376 |
Other pulmonary | 339 (2.2) | 118 (3.8) | 68 (2.0) | 91 (2.3) | 62 (1.2) | .393 |
Organ transplant | 229 (1.5) | 65 (2.1) | 45 (1.4) | 57 (1.5) | 62 (1.2) | .432 |
Congenital heart disease | 33 (0.2) | 11 (0.4) | 4 (0.1) | 11 (0.3) | 7 (0.1) | .471 |
Pulmonary arterial hypertension | 57 (0.4) | 27 (0.9) | 8 (0.2) | 19 (0.5) | 3 (0.1) | .441 |
No medical history | 2704 (17.6) | 543 (17.4) | 592 (17.8) | 639 (16.5) | 930 (18.5) | .349 |
CABG = coronary artery bypass grafting; COPD = chronic obstructive pulmonary disorder; COVID-19 = coronavirus disease 2019; DVT = deep vein thrombosis; HIV = human immunodeficiency virus; ILD = interstitial lung disease; MI = myocardial infarction; PCI = percutaneous coronary intervention; SD = standard deviation; TIA = transient ischemic attack.