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. 2021 Jul 31;134(11):1380–1388.e3. doi: 10.1016/j.amjmed.2021.06.034

Supplementary Table 3.

Characteristics of Patients Across Hospital COVID-19 Case Growth Quartiles

Overall Q1 Q2 Q3 Q4 P Values
Number of patients 15,329 3114 3318 3875 5022
Age (mean [SD]) 61.29 (17.71) 58.69 (18.12) 60.76 (18.17) 63.17 (17.38) 61.81 (17.17) <.001
Race (%)
 Black 7643 (49.9) 1599 (51.3) 1876 (56.5) 1783 (46.0) 2385 (47.5) .267
 White 4101 (26.8) 958 (30.8) 995 (30.0) 1091 (28.2) 1057 (21.0)
 Others 3569 (23.3) 557 (17.9) 446 (13.4) 989 (25.5) 1577 (31.4)
 Missing 16 (0.1) 0 (0.0) 1 (0.0) 12 (0.3) 3 (0.1)
Female sex 8357 (54.5) 1598 (51.3) 1776 (53.5) 2069 (53.4) 2914 (58.0) .28
Atrial fibrillation/flutter 1407 (9.2) 299 (9.6) 349 (10.5) 403 (10.4) 356 (7.1) .36
Cancer 2023 (13.2) 385 (12.4) 387 (11.7) 438 (11.3) 813 (16.2) .393
Cerebrovascular disease (stroke or TIA) 1989 (13.0) 307 (9.9) 367 (11.1) 348 (9.0) 967 (19.3) .437
Currently on dialysis 534 (3.5) 94 (3.0) 131 (3.9) 137 (3.5) 172 (3.4) .431
Diabetes mellitus 5400 (35.2) 1191 (38.2) 1247 (37.6) 1420 (36.6) 1542 (30.7) .264
Dyslipidemia 5215 (34.0) 1066 (34.2) 1257 (7.9) 1506 (38.9) 1386 (7.6) .27
Heart failure 1686 (11.0) 396 (12.7) 445 (13.4) 456 (11.8) 389 (7.7) .328
Hypertension 8863 (57.8) 1890 (60.7) 2028 (61.1) 2428 (62.7) 2517 (50.1) .228
Peripheral artery disease 414 (2.7) 104 (3.3) 85 (2.6) 136 (3.5) 89 (1.8) .412
Prior CABG 420 (2.7) 81 (2.6) 118 (3.6) 106 (2.7) 115 (2.3) .424
Prior MI 772 (5.0) 209 (6.7) 206 (6.2) 210 (5.4) 147 (2.9) .361
Prior PCI 662 (4.3) 140 (4.5) 177 (5.3) 178 (4.6) 167 (3.3) .398
Chronic kidney disease 1942 (12.7) 448 (14.4) 429 (12.9) 538 (13.9) 527 (10.5) .338
DVT 475 (3.1) 104 (3.3) 122 (3.7) 128 (3.3) 121 (2.4) .413
History of smoking 1013 (6.6) 235 (7.5) 312 (9.4) 206 (5.3) 260 (5.2) .359
Immune disorders 703 (4.6) 129 (4.1) 151 (4.6) 242 (6.2) 181 (3.6) .416
HIV 167 (1.1) 22 (0.7) 34 (1.0) 50 (1.3) 61 (1.2) .476
Lupus 88 (0.6) 21 (0.7) 20 (0.6) 24 (0.6) 23 (0.5) .461
Rheumatoid 174 (1.1) 33 (1.1) 49 (1.5) 58 (1.5) 34 (0.7) .447
Other immune disorder 285 (1.9) 60 (1.9) 53 (1.6) 120 (3.1) 52 (1.0) .437
Pulmonary embolism 301 (2.0) 80 (2.6) 77 (2.3) 74 (1.9) 70 (1.4) .417
Pulmonary disease 2703 (17.6) 574 (18.4) 630 (19.0) 767 (19.8) 732 (14.6) .322
COPD 1215 (7.9) 232 (7.5) 333 (10.0) 331 (8.5) 319 (6.4) .375
ILD 62 (0.4) 9 (0.3) 17 (0.5) 24 (0.6) 12 (0.2) .474
Asthma 1373 (9.0) 290 (9.3) 286 (8.6) 409 (10.6) 388 (7.7) .376
Other pulmonary 339 (2.2) 118 (3.8) 68 (2.0) 91 (2.3) 62 (1.2) .393
Organ transplant 229 (1.5) 65 (2.1) 45 (1.4) 57 (1.5) 62 (1.2) .432
Congenital heart disease 33 (0.2) 11 (0.4) 4 (0.1) 11 (0.3) 7 (0.1) .471
Pulmonary arterial hypertension 57 (0.4) 27 (0.9) 8 (0.2) 19 (0.5) 3 (0.1) .441
No medical history 2704 (17.6) 543 (17.4) 592 (17.8) 639 (16.5) 930 (18.5) .349

CABG = coronary artery bypass grafting; COPD = chronic obstructive pulmonary disorder; COVID-19 = coronavirus disease 2019; DVT = deep vein thrombosis; HIV = human immunodeficiency virus; ILD = interstitial lung disease; MI = myocardial infarction; PCI = percutaneous coronary intervention; SD = standard deviation; TIA = transient ischemic attack.