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. 2021 Jul 23;2021:9920826. doi: 10.1155/2021/9920826

Table 1.

Effect of APLE on organ weight/bodyweight ratios and bodyweight change.

Organ weight/body weight ratio Body weight (g)
Spleen Liver Kidney Pancreas Initial Final % change in body weight
Control 0.005 ± 3.7 × 10−5 0.043 ± 3.0 × 10−4 0.005 ± 3.2 × 10−4 0.004 ± 2.6 × 10−5 153.6 ± 14.5 154.5 ± 17.4 0.58
Model 0.005 ± 1.6 × 10−4 0.032 ± 1.0 × 10−3 0.004 ± 1.3 × 10−4 0.005 ± 1.6 × 10−4 167.4 ± 23.8 156.4 ± 8.0 -6.57a
Metformin (mg/kg) 0.005 ± 1.2 × 10−4 0.042 ± 1.0 × 10−3 0.004 ± 1.0 × 10−4 0.002 ± 5.5 × 10−4 167.2 ± 52.9 163.1 ± 11.2 -0.02ns
APLE (mg/kg)
100 0.006 ± 1.6 × 10−4 0.050 ± 1.0 × 10−3 0.006 ± 1.6 × 10−4 0.005 ± 1.4 × 10−4 138.5 ± 32.4 145.5 ± 62.6 5.10b
200 0.006 ± 2.3 × 10−4 0.055 ± 2.0 × 10−3 0.006 ± 2.4 × 10−4 0.004 ± 1.4 × 10−4 146.6 ± 43.5 140.9 ± 21.5 -3.86ns
400 0.005 ± 2.3 × 10−4 0.031 ± 1.0 × 10−3 0.003 ± 1.3 × 10−4 0.005 ± 2.0 × 10−4 156.2 ± 23.0 154.6 ± 24.9 -0.99ns

Received normal saline; APLE: Abrus precatorius leaf extract (APLE); ns: not significant; aP ≤ 0.05 (model vs. control); bP ≤ 0.05 (APLE and metformin vs. model).