Table 3.
Effect of APLE on number of pancreatic islets and median pancreatic area of Alloxan/nicotinamide-induced diabetic rats.
| Treatment groups | Number of islets | Median area (×103μm2; Q1-Q3) | Average rank |
|---|---|---|---|
| Control | 16 | 5.299 (2.047-9.996) | 65.0 |
| Model | 16ns | 3.131 (1.445-6.142)a | 34.9 |
| Metformin (300 mg/kg) | 18ns | 4.336 (2.348-7.587)ns | 50.6 |
| APLE (mg/kg) | |||
| 100 | 27b | 7.467 (5.299-9.635)b | 76.0 |
| 200 | 25b | 7.949 (6.624-9.153)b | 83.2 |
| 400 | 35b | 7.949 (6.744-9.394)b | 80.3 |
a P ≤ 0.05 (model vs control); bP ≤ 0.05 (APLE and metformin vs. model); APLE: Abrus precatorius leaf extract; ns: not significant.