Table 2.

Ventilatory parameters of participants after 6 days of placebo vs. mirtazapine treatment

	Placebo	Mirtazapine
V̇e, L/min	7.2 ± 2.1	8.4 ± 2.5
VT, L	0.6 ± 0.2	0.6 ± 0.2
f, breaths/min	12.8 ± 2.3	13.6 ± 3.1
VMAX Insp, L/s	0.4 ± 0.1	0.4 ± 0.1
TI, s	2.0 ± 0.5	2.0 ± 0.4
TE, s	2.8 ± 0.6	2.6 ± 0.8
TTot, s	4.8 ± 0.9	4.6 ± 1.1
TI/TTot	0.4 ± 0.1	0.4 ± 0.1
PETCO2, mmHg	40.6 ± 4.2	40.3 ± 4.8
$\text{S}{\text{a}}_{{\text{O}}_2}$, %	96.4 ± 1.5	96.2 ± 1.4

Values are presented as means ± SD; n = 10 participants. Measures were determined during non-REM stable sleep during normal breathing on room air. f, respiratory rate; PET_CO2, end-tidal CO₂ partial pressure; REM, rapid eye movement; $\text{S}{\text{a}}_{{\text{O}}_2}$, oxygen saturation; T_I, inspiratory duration; T_E, expiratory duration; T_Tot, breath duration; T_I/t_tot, fractional inspiratory time; V̇e, minute ventilation; V_{MAX insp}, maximal inspiratory pressure; V_T, tidal volume.