Table 2.
Socioeconomic pathways for the genetic association to later life cognition (coefficient, p).
| Model 1 | Model 2 | Model 3 | Model 4 | Model 5 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Intercept | 26.868 | <.0001 | 17.907 | <.0001 | 26.769 | <.0001 | 27.633 | <.0001 | 18.599 | <.0001 |
| Polygenic risk score | 0.419 | <.0001 | 0.302 | <.0001 | 0.410 | <.0001 | 0.421 | <.0001 | 0.305 | <.0001 |
| Years of Education | 0.562 | <.0001 | 0.543 | <.0001 | ||||||
| Wealth (Millions$) | 0.315 | <.0001 | 0.128 | <.0001 | ||||||
| Neighborhood Poverty | −4.944 | <.0001 | −2.710 | <.0006 | ||||||
| Age (2016) | −0.161 | <.0001 | −0.144 | <.0001 | −0.162 | <.0001 | −0.161 | <.0001 | −0.145 | <.0001 |
| Sex [Female = 1] | 0.550 | <.0001 | 0.763 | <.0001 | 0.588 | <.0001 | 0.526 | <.0001 | 0.754 | <.0001 |
| R squared | 0.167 | 0.263 | 0.176 | 0.171 | 0.266 | |||||
Note: All data from the Health and Retirement Study (n = 7,493). All coefficients were yielded from simple linear regressions.