Table 6.
Firefighter PBDE serum concentrationsA (ng/g lipid) by job assignment compared to the general population (GP).
Pre-fire Serum Concentration | Post-fire Serum Concentration | |||||||
---|---|---|---|---|---|---|---|---|
Analyte | Job assignment | N (No. < LODB) |
GM (ng/g lipid) (GSD) |
P-value (vs GP) |
N (No. < LODB) |
GM (ng/g lipid) (GSD) |
P-value (vs GP) |
P-value (Pre vs Post) |
BDE-28 | All firefighters | 36 (4) | 0.53 (2.25) | 0.029D | 36 (2) | 0.54 (2.15) | 0.027D | 0.922 |
Exterior | 12 (2) | 0.43 (1.88) | 0.016D | 12 (0) | 0.43 (1.81) | 0.011D | 0.498 | |
Interior | 12 (2) | 0.47 (2.06) | 0.065 | 12 (2) | 0.47 (1.87) | 0.039D | 0.226 | |
Overhaul | 12 (0) | 0.74 (2.69) | 0.928 | 12 (0) | 0.77 (2.59) | 0.823 | 0.984 | |
General PopulationC | 1637 (178) | 0.72 (1.78) | Reference | ** | ** | Reference | ||
BDE-47 | All firefighters | 36 (0) | 8.49 (2.59) | 0.008D | 36 (0) | 8.37 (2.57) | 0.006D | 0.869 |
Exterior | 12 (0) | 5.94 (1.88) | 0.001D | 12 (0) | 5.73 (1.86) | <0.001D | 0.172 | |
Interior | 12 (0) | 7.58 (2.28) | 0.038D | 12 (0) | 7.60 (2.23) | 0.034D | 0.447 | |
Overhaul | 12 (0) | 13.59 (3.29) | 0.955 | 12 (0) | 13.47 (3.25) | 0.974 | 0.921 | |
General PopulationC | 1637 (0) | 13.32 (1.89) | Reference | ** | ** | Reference | ||
BDE-99 | All firefighters | 36 (0) | 1.58 (2.80) | 0.007D | 36 (0) | 1.49 (2.76) | 0.003D | 0.816 |
Exterior | 12 (0) | 1.08 (2.01) | 0.001D | 12 (0) | 0.95 (2.01) | <0.001D | 0.081 | |
Interior | 12 (0) | 1.32 (2.62) | 0.035D | 12 (0) | 1.31 (2.46) | 0.024D | 0.135 | |
Overhaul | 12 (0) | 2.76 (3.30) | 0.852 | 12 (0) | 2.68 (3.23) | 0.918 | 0.899 | |
General PopulationC | 1637 (0) | 2.59 (2.12) | Reference | ** | ** | Reference | ||
BDE-100 | All firefighters | 36 (1) | 1.58 (2.52) | <0.001D | 36 (0) | 1.67 (2.28) | <0.001D | 0.992 |
Exterior | 12 (0) | 1.24 (1.56) | <0.001D | 12 (0) | 1.19 (1.52) | <0.001D | 0.091 | |
Interior | 12 (0) | 1.60 (2.08) | 0.017D | 12 (0) | 1.54 (2.10) | 0.014D | 0.204 | |
Overhaul | 12 (1) | 1.99 (3.91) | 0.361 | 12 (0) | 2.52 (2.87) | 0.657 | 0.949 | |
General PopulationC | 1637 (0) | 2.90 (1.88) | Reference | ** | ** | Reference | ||
BDE-153 | All firefighters | 36 (0) | 5.66 (2.42) | <.001D | 36 (0) | 5.53 (2.44) | <0.001D | 0.907 |
Exterior | 12 (0) | 4.61 (2.22) | 0.008D | 12 (0) | 4.45 (2.23) | 0.006D | 0.347 | |
Interior | 12 (0) | 4.37 (2.05) | 0.003D | 12 (0) | 4.33 (2.09) | 0.003D | 0.962 | |
Overhaul | 12 (0) | 9.00 (2.68) | 0.769 | 12 (0) | 8.80 (2.72) | 0.715 | 0.790 | |
General PopulationC | 1637 (0) | 9.81 (1.93) | Reference | ** | ** | Reference | ||
BDE-209 | All firefighters | 36 (2) | 2.91 (1.79) | <0.001E | 36 (0) | 3.01 (1.57) | <0.001E | 0.687 |
Exterior | 12 (1) | 2.35 (1.71) | 0.191 | 12 (0) | 2.69 (1.56) | 0.020E | 0.359 | |
Interior | 12 (1) | 2.75 (1.87) | 0.062 | 12 (0) | 2.86 (1.61) | 0.012E | 0.720 | |
Overhaul | 12 (0) | 3.82 (1.66) | <0.001E | 12 (0) | 3.53 (1.53) | <0.001E | 0.257 | |
General PopulationC | 1637 (27) | 1.89 (1.64) | Reference | ** | ** | Reference |
PBDEs with less than 60% detection rate are summarized in Supplemental Materials (S4).
LOD: limit of detection. Observations below the LOD were substituted using LOD/square root of 2.
The data are from the National Health and Nutrition Examination Survey (NHANES) (2020). 2015–2016 data documentation, codebook, and frequencies. Brominated Flame Retardants (BFRs) - Pooled Samples (BFRPOL_I). Available at https://wwwn.cdc.eov/Nchs/Nhanes/2015-2016/BFRPQL_I.htm.Accessed12November2020.
Results were significantly lower than the general population.
Results were significantly higher than the general population.
GM and GSD of general population were listed in the pre serum columns.