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. 2021 Feb 1;30(3-4):255–263. doi: 10.1038/s41434-021-00226-0

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© The Author(s), under exclusive licence to Springer Nature Limited part of Springer Nature 2021

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Fig. 3 — A–D Gene expression heatmaps for (A) microglia, (B) neurons, (C) oligodendrocytes, and (D) astrocytes. Each column represents a single-cell and each row represents a gene of interest. Selected genes for each cell type are significantly (p-adjusted < 0.05) upregulated or downregulated at 0.2 MPa or 0.4 MPa compared to control. Expression levels are presented as row-normalized z-scores according to the key. Numbers in parenthesis indicate the total number of cells (columns) or genes (rows) presented. E Magnitude of significant (p adjusted < 0.05) differential gene expression (upregulated + downregulated) for each cell type at each pressure vs control cells.