Ketamine did not modulate behavior in the elevated zero maze in either sex. Behavior (48 hours post-injection) was automatically scored by computer and parsed into: A, total distance traveled; B, open arm distance; C, open arm frequency; D, open arm duration. UCS-exposed animals exhibited decreases in measures B-D, irrespective of ketamine or sex. Error bars: ± SEM. Three-way ANOVA, main effect of stress: * p < 0.05, ** p < 0.01.