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. Author manuscript; available in PMC: 2022 Jan 20.
Published in final edited form as: Stress. 2021 Feb 1;24(6):857–865. doi: 10.1080/10253890.2021.1871600

Figure 5.

Figure 5.

Chronic stress and ketamine interacted to modulate the corticosterone response to acute injection stress. Plasma corticosterone was measured 30 minutes after ketamine or vehicle injection, by tail vein puncture. Prior UCS exposure suppressed corticosterone irrespective of sex. There was also a significant stress by drug interaction. Error bars: ± SEM. Three-way ANOVA, main effect of stress: ** p < 0.01, stress x drug interaction: * p < 0.05.