Fig. 2. Association of phosphopeptide modules with clinical and pathologic phenotypes.

a For each module the association with small spine density, synaptic protein levels and SES are shown. Significant correlations with synaptic protein levels were defined as q < 0.05, and the percent of those significantly correlated synaptic proteins that were negatively correlated with each module is shown (% with r < 0). b pS1782 negatively correlates (r = −0.61, p = 0.0002) with dendritic spine density. NPC nonpsychiatric control, Sz subjects grouped by MAP2 immunoreactivity as either normal (MAP2-IR_NL) or low (MAP2-IR_LOW).