Table 2.
Univariate and multivariate analysis of risk factors associated with 30-day mortality in hematological patients with SM bacteremia
| Characteristics | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value | |
| Age | 1.014 (0.992–1.036) | 0.205 | ||
| Polymicrobial bacteremia | 1.265 (0.595–2.688) | 0.541 | ||
| Neutropenia | 5.100 (1.781–14.606) | 0.002 | 5.857 (1.956–17.538) | 0.002 |
| Hemoglobin < 60 g/L | 1.585 (0.812–3.092) | 0.177 | ||
| Platelet< 50,000/uL | 5.720 (0.781–41.863) | 0.086 | ||
| Fibrinogen< 2 g/L | 1.525 (0.718–3.241) | 0.273 | ||
| PT > 13.5 s | 2.575 (1.326–5.002) | 0.005 | ||
| APTT> 33.5 s | 1.694 (0.798–3.595) | 0.170 | ||
| D-Dimer>700μg/L FEU | 1.609 (0.626–4.133) | 0.323 | ||
| Albumin< 30 g/L | 1.336 (0.699–2.552) | 0.381 | ||
| Globulin< 20 g/L | 2.400 (1.241–4.641) | 0.009 | 2.931 (1.478–5.811) | 0.002 |
| C-reactive protein≥10 mg/dl | 1.397 (0.693–2.815) | 0.349 | ||
| Procalcitonin > 0.5μg/L | 1.827 (0.799–4.175) | 0.153 | ||
| HSCT | 1.385 (0.669–2.868) | 0.381 | ||
| Inadequate initial antimicrobial treatment | 2.014 (0.972–4.175) | 0.060 | 2.974 (1.368–6.465) | 0.006 |
| Central venous catheter | 1.183 (0.460–3.041) | 0.728 | ||
| Prior tigecycline therapy within 1 month | 1.043 (0.544–2.001) | 0.898 | ||
| Prior carbapenem therapy within 1 month | 0.946 (0.394–2.271) | 0.902 | ||
| Hemorrhagic pneumonia | 2.496 (1.268–4.914) | 0.008 | 2.316 (1.140–4.705) | 0.020 |
Abbreviations: CI, confidence interval; PT, prothrombin time; APTT, activated partial thromboplastin time; HSCT, hematopoietic stem cell transplantation