Table 4.
Univariate and multivariate analysis of risk factors associated with hemorrhagic pneumonia in hematological patients with SM bacteremia
| Characteristics | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| OR (95% CI) | P-value | OR (95% CI) | P-value | |
| Age | 1.030 (0.994–1.068) | 0.105 | ||
| Polymicrobial bacteremia | 1.917 (0.490–7.494) | 0.350 | ||
| Neutropenia | 5.176 (1.252–21.411) | 0.023 | 4.988 (1.040–23.920) | 0.045 |
| Hemoglobin < 60 g/L | 1.261 (0.433–3.668) | 0.671 | ||
| Platelet< 50,000/uL | 1.500 (0.230–9.763) | 0.671 | ||
| Fibrinogen< 2 g/L | 2.100 (0.537–8.217) | 0.286 | ||
| PT > 13.5 s | 2.692 (0.883–8.206) | 0.082 | ||
| APTT> 33.5 s | 2.265 (0.694–7.389) | 0.175 | ||
| D-Dimer>700μg/L FEU | 1.568 (0.389–6.319) | 0.527 | ||
| Albumin< 30 g/L | 1.440 (0.487–4.255) | 0.509 | ||
| Globulin< 20 g/L | 1.261 (0.433–3.668) | 0.671 | ||
| C-reactive protein≥10 mg/dl | 1.973 (0.638–6.106) | 0.238 | ||
| Procalcitonin > 0.5μg/L | 9.375 (1.849–47.522) | 0.007 | 11.322 (1.943–65.956) | 0.007 |
| HSCT | 1.167 (0.335–4.060) | 0.809 | ||
| Inadequate initial antimicrobial treatment | 1.451 (0.481–4.377) | 0.508 | ||
| Central venous catheter | 2.717 (0.479–15.402) | 0.259 | ||
| Prior tigecycline therapy within 1 month | 4.364 (1.383–13.772) | 0.012 | 4.482 (1.135–17.702) | 0.032 |
| Prior carbapenem therapy within 1 month | 1.250 (0.297–5.256) | 0.761 | ||
Abbreviations: OR odds rate, CI confidence interval, PT prothrombin time; APTT activated partial thromboplastin time, HSCT hematopoietic stem cell transplantation