Table 4.
Correlation between exosome AEBP1 level and clinical parameters in DKD patients
| Clinical parameters | Exosome AEBP1 level | |
|---|---|---|
| R value | P value | |
| Age (yrs) | − 0.283 | 0.307 |
| BMI | − 0.242 | 0.384 |
| SBP (mmHg) | − 0.309 | 0.263 |
| DBP (mmHg) | − 0.140 | 0.619 |
| HbA1c (%) | − 0.062 | 0.827 |
| eGFR (MDRD, ml/min/1.73m2) | − 0.614 | 0.0015 |
| eGFR (CKD-EPI, ml/min/1.73m2) | − 0.59 | 0.020 |
| BUN (mmol/L) | 0.298 | 0.280 |
| Creatinine (µmol/L) | 0.629 | 0.012 |
| TC (mmol/L) | − 0.170 | 0.545 |
| TG (mmol) | − 0.161 | 0.567 |
| LDL (mmol/L) | − 0.556 | 0.031 |
| HDL (mmol/L) | − 0.034 | 0.905 |
| 24-h urine protein (g/d) | 0.559 | 0.0304 |
| Urine protein to creatinine ratio | − 0.079 | 0.778 |
| Albumin (g/L) | − 0.335 | 0.222 |
| Albumin/creatinine ratio (mg/g) | 0.258 | 0.374 |
| Urine β2MG (mg/L) | − 0.003 | 0.993 |
| Urine RBP (mg/L) | 0.357 | 0.255 |
| Urine CYC (mg/L) | − 0.189 | 0.667 |
| Serum CYC (mg/L) | 0.656 | 0.008 |
| Hemoglobin (g/L) | − 0.424 | 0.116 |
| WBC (109/L) | − 0.101 | 0.719 |
| Monocytes (109/L) | − 0.068 | 0.810 |
| Lymphocytes (109/L) | − 0.157 | 0.576 |
| Neutrophils (109/L) | − 0.041 | 0.885 |
| hsCRP (mg/L) | 0.474 | 0.074 |
Bold indicates p < 0.05
BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, T2DM type II diabetes mellitus, HbA1c glycated hemoglobin, MDRD The Modification of Diet in Renal Disease, CKD-EPI The Chronic Kidney Disease Epidemiology Collaboration, TC total cholesterol, TG triglycerides, HDL high density lipoprotein, LDL low-density lipoprotein cholesterol, BUN blood urea nitrogen, RBP retinol-binding protein, CYC cystatin-C, WBC White Blood Cell