Table 1.
Recommendations to prescribers from the antimicrobial stewardship team
1) | Order of culture examinations | ・Identification of microbial pathogens and implementation of susceptibility tests before administration of parenteral antimicrobials. |
2) | Selection of antimicrobials |
・Selection of antimicrobials for empirical initial antimicrobial therapy. ・Changes in antimicrobials based on the results of susceptibility tests (not including de-escalation). |
3) | Dose of antimicrobials | ・Dose optimization based on the severity of disease and the renal function of patients. |
4) | Duration of antimicrobial therapy | ・Recommendation to discontinue antimicrobial therapy. |
5) | De-escalation | ・Change in excessively broad therapy to more targeted antimicrobial therapy. |
6) | Therapeutic drug monitoring | ・Dose and/or dosing interval recommendation based on the results of a pharmacokinetic analysis. |
7) | Others | ・Other recommendations concerning infectious disease therapy. |