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. 2021 Aug 1;7:25. doi: 10.1186/s40780-021-00206-x

Table 4.

Changes in AUD, DOT, and the AUD/DOT ratio between pre- and post-AS periods

Carbapenem TAZ/PIPC
pre-AS post-AS p-value pre-AS post-AS p-value
AUD 8.28 ± 3.39 3.67 ± 1.73 < 0.05 15.05 ± 5.91 8.55 ± 3.47 < 0.05
DOT 21.62 ± 7.23 5.88 ± 1.76 < 0.01 20.93 ± 8.76 12.65 ± 4.96 < 0.05
AUD/DOT 0.37 ± 0.07 0.60 ± 0.12 < 0.01 0.73 ± 0.08 0.67 ± 0.07 0.15

Values are presented as means±SD

AUD: Antimicrobial use density (DDDs/1000 patient-days), DOT: Days of therapy (DOTs/1000 patient-days)

Data were analyzed using the Mann-Whitney U-test