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. 2021 Jul 31;16:332. doi: 10.1186/s13023-021-01965-4

Table 2.

Unadjusted and adjusted FEV1 percent predicted by genotype. #

N,% * (BLx, NHC) Delta FEV1 percent predicted unadjusted (CI)** p Delta FEV1 percent predicted adjusted (CI) p
Heterozygous F508 9 (23%), 97 (43%) − 16.92 (− 33.01, − 0.82) 0.040 − 15.57 (− 32.31, 1.16) 0.068
Homozygous F508 13 (38%), 59 (28%) − 4.60 (− 18.77, 9.55) 0.520 − 0.67 (− 17.42, 16.08) 0.937
No F508 mutation 13 (38%), 49 (24%) − 11.70 (− 27.21, 3.82) 0.137 − 9.65 (− 25.15, 7.84) 0.273

*Missing data in 22 patients

**Reflects difference in FEV1 percent predicted of BLx group compared with NHC

# Patients’ gender, age, age at diagnosis, presence of diabetes, median household income based on zip code of residence, and insurance type (private/Medicare vs. public (Medicaid)) were included in the model to adjust for potential confounding