Table 2.
N,% * (BLx, NHC) | Delta FEV1 percent predicted unadjusted (CI)** | p | Delta FEV1 percent predicted adjusted (CI) | p | |
---|---|---|---|---|---|
Heterozygous F508 | 9 (23%), 97 (43%) | − 16.92 (− 33.01, − 0.82) | 0.040 | − 15.57 (− 32.31, 1.16) | 0.068 |
Homozygous F508 | 13 (38%), 59 (28%) | − 4.60 (− 18.77, 9.55) | 0.520 | − 0.67 (− 17.42, 16.08) | 0.937 |
No F508 mutation | 13 (38%), 49 (24%) | − 11.70 (− 27.21, 3.82) | 0.137 | − 9.65 (− 25.15, 7.84) | 0.273 |
*Missing data in 22 patients
**Reflects difference in FEV1 percent predicted of BLx group compared with NHC
# Patients’ gender, age, age at diagnosis, presence of diabetes, median household income based on zip code of residence, and insurance type (private/Medicare vs. public (Medicaid)) were included in the model to adjust for potential confounding