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. 2021 Jul 29;9:e11893. doi: 10.7717/peerj.11893

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© 2021 Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

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(A) The mRNA expression levels of HNRNPC in esophageal cancer cell lines (KYSE30 and TE-1) and normal esophageal epithelial cell line HEEC were determined by qRT-PCR. (B) The HNRNPC knockdown efficiency was confirmed at the mRNA levels in KYSE30 and TE-1 cells by qRT-PCR. (C–D) MTT assay was performed to determine the cell proliferation in KYSE30 (C) and TE-1 cells (D). (E–F) Transwell assay was performed to assess the cell migration and invasion capacity in KYSE30 (E) and TE-1 (F) cells. **P < 0.01; ***P < 0.001; ****P < 0.0001.