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. 2021 Jul 29;9:e11893. doi: 10.7717/peerj.11893

Figure 7. miR-186 targeted HNRNPC and suppressed HNRNPC expression.

Figure 7

(A) The relative expression of 4 miRNAs (miR-186, miR-320c, miR-320d, miR-320b) were detected in esophageal cancer cell lines (KYSE30 and TE-1) and normal esophageal epithelial cell line HEEC. (B) Potential binding site of miR-186 in HNRNPC. Detection of miR-186 mimics on luciferase activity of wild-type or mutant HNRNPC by luciferase reporter assay. (C–D) The mRNA expression levels of HNRNPC were assessed by qRT-PCR. *P < 0.05; **P < 0.01; ****P < 0.0001.