Figure 6.
A summary of regulation of lncRNAs in GC through different signaling pathways, including the PI3K/AKT, STAT3, mTOR, MAPK and Wnt/β-catenin signaling pathways. (1) LncRNA AK023391 96 and lncRNA ADAMTS9-AS2 97 participated in GC development by affecting PI3K/AKT signaling pathway. (2) LncRNA PVT1 99, SNHG16 100, and OLC8 50 participated in GC development by affecting STAT3 signaling pathway. (3) LncRNA LINC01419 105, HAGLROS 106, NORAD 107 participated in GC development by affecting mTOR signaling pathway. (4) LncRNA AOC4P 109, CARlo-5 110, KCNK15-AS1 111 participated in GC development by affecting MAPK signaling pathway. (5) Some lncRNAs enhanced GC progression by activating other signaling pathways, including Wnt/β-catenin signaling pathways 112.