Figure 7.
CXCL10 increases tumor growth and CC cell metastasis in vivo (A) Typical images showing tumor masses collected in nude mice transplanted with SW480, SW620, SW480-Vector, SW620-Vector, SW480-CXCL10, SW620-CXCL10 cells. Tumor length and width were detected using a ruler per 3 days, then tumor size was determined (length2×width2×0.5). (B) The cell proliferation marker Ki-67 within CC was measured through immunohistochemistry, the Ki-67-positive cell proportion was calculated. the scale bars represent 100 μm. (C) The lung metastatic lesion number was used to analyze and calculate by H&E staining. (Black arrows indicate metastatic sites). the scale bars represent 100 μm. Every bar chart stands for mean ±SD (n=3). **p < 0.01 by Sidak multiple comparison test.