Central Illustration.

The Identification of Genetic Variants Influencing Coronary Artery Disease Risk Affects Several Fields

From a deeper knowledge of the: 1) pathophysiological processes, 2) novel treatment targets were identified; 3) the interplay between genetic factors and traditional risk factors such as obesity, hypertension, smoking, or hyperlipidemia but also noise and air pollution is the subject of extensive research. Finally, genetic risk scores may in the future 4) improve risk prediction and lead to the development of 5) individualized treatment strategies, the cornerstone of precision medicine. PCSK9 = proprotein convertase subtilisin/kexin type 9. Modified image material available at Servier Medical Art under a Creative Commons Attribution 3.0 Unsupported License.