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The area under the receiver operating characteristic curves of tumor markers for the diagnosis of very early and early-stage hepatocellular carcinom in the total population. AUROC: Area under the receiver operating characteristic curve; HCC: Hepatocellular carcinoma; AFP: Alpha-fetoprotein; AFP-L3: Lens culinaris agglutinin-reactive fraction of AFP; PIVKA-II: Protein induced by vitamin K absence or antagonist-II; ALPs: AFP, AFP-L3 fraction, and PIVKA-II.
