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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Biometrics. 2021 Feb 16;78(2):730–741. doi: 10.1111/biom.13436

FIGURE 1.

FIGURE 1

Mediation causal structure with outcome Y, exposure A, mediator M, baseline confounder(s) Z, and exposure-induced mediator-outcome confounder(s) W. The controlled direct effect captures the AY effect when M is fixed to some m. Natural direct and indirect effects are not identified under this structure due to the AW arrow, but randomized interventional analogs are identified