Table 1.
Clinical characteristics, laboratory parameters, and ventilation settings of VA-ECMO patients on day 0.
| Parameter | VA-ECMO patients |
|---|---|
| Patients, n (%) | 22 (100) |
| Age, y (Q1-Q3) | 63 (52-73) |
| Survivors, n (%) | 11 (50) |
| Female, n (%) | 8 (37) |
| Type of VA-ECMO, n (%) | |
| Stöckert Sorin Maquet Deltastream CARL |
12 (55) 7 (32) 2 (9) 1 (4) |
| Days on ECMO (median, Q1-Q3) | 6.0 (3.8-7.0) |
| ECMO Blood Flow (l/min, Q1-Q3) | 4.3 (3.8-4.8) |
| Indication for VA-ECMO, n (%) | |
| Cardiogenic shock (due to) | 15 (68) |
| Postoperative/postinterventional | 7 (32) |
| Myocardial infarction | 2 (9) |
| Ischemic cardiomyopathy | 1 (4) |
| Unknown cardiomyopathy | 1 (4) |
| Endocarditis | 1 (4) |
| Pulmonary embolism | 1 (4) |
| After CPR | 1 (4) |
| Mitral regurgitation | 1 (4) |
| eCPR (due to) | 1 (4) |
| Myocardial ischemia | 1 (4) |
| Unknown | 1 (4) |
| Cardiovascular disease, n (%) | 15 (68) |
| Atrial fibrillation, n (%) | 8 (36) |
| Diabetes mellitus, n (%) | 2 (9) |
| Hypertension, n (%) | 7 (32) |
| Active smoker, n (%) | 3 (14) |
| Hypercholesterolemia, n (%) | 4 (18) |
| Cancer, n (%) | 0 (0) |
| Acute renal failure, n (%) | 15 (68) |
| Continuous hemodialysis, n (%) | 9 (41) |
| Heparin, n (%) | 21 (95) |
| Dual anti-platelet therapy, n (%) | 9 (41) |
| Immunosuppression, n (%) | 1 (4) |
| Received transfusions, n (%) | 22 (100) |
| Cytosorb, n (%) | 1 (4) |
| Mechanical ventilation, n (%) | 22 (100) |
| SOFA score (Q1-Q3) | 11.0 (9.0-13.0) |
| WBC (×103 /μl, Q1-Q3) | 9.6 (7.5-14.0) |
| Platelets (×103 /μl, Q1-Q3) | 102.0 (74.0-140.0) |
| Hb (g/dl, Q1-Q3) | 8.7 (8.3-9.4) |
| Creatinine (mg/dl, Q1-Q3) | 1.7 (1.0-2.5) |
| Urea (mg/dl, Q1-Q3) | 58.0 (33.0-77.0) |
| Bilirubin (mg/dl, Q1-Q3) | 2.4 (1.5-3.3) |
| AST (U/l, Q1-Q3) | 161.0 (70.3-437.5) |
| ALT (U/l, Q1-Q3) | 63 (25.3-123.8) |
| CRP (mg/l, Q1-Q3) | 54.1 (25.3-101.0) |
| IL-6 (pg/ml) | 378.0 (297.5-1007) |
| Ferritin (ng/ml, Q1-Q3) | 371 (203.0-4163) |
| Lactate (mmol/l, Q1-Q3) | 3.25 (1.4-5.9) |
| paO2 (mmHg, Q1-Q3) | 111 (76.8-167.3) |
| paCO2 (mmHg, Q1-Q3) | 39.4 (35.3-45.5) |
| FiO (%, Q1-Q3) | 50.0 (40.0-50.0) |
| PEEP (mbar, Q1-Q3) | 8.0 (7.0-10.0) |
| Respiratory rate (/min, Q1-Q3) | 14.0 (12.0-18.0) |
Data are presented as median (interquartile range, Q1-Q3) or number of patients (%). Denominator of the percentage is the total number of subjects in the group. Parameters from the patient data management system that were closest to the time point of blood sampling for flow cytometric analysis are presented. ALT, alanine aminotransferase; AST, aspartate aminotransferase; CRP, C-reactive protein; eCPR, extracorporeal cardiopulmonary resuscitation; FiO, fraction of inspired oxygen; PEEP, positive end-expiratory pressure; SOFA, sequential organ failure assessment score; WBC, white blood cells.