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Postmortem neuropathologic evaluation showing prominent clasmatodendrosis in a patient with a history of acute lymphoblastic leukemia treated with anti-CD19 CAR T-cell therapy complicated by fulminant cerebral edema. Beading and fragmentation of astrocytic processes (highlighted by GFAP immunostains) were seen in sections of cortex (A, 200x; B, 400x) and were accentuated around blood vessels (C, 600x).
