Bovine serum albumin (BSA) denaturation inhibitory activity of the extracts (ie, n-hexane, ethanol, and aqueous) of Gynura procumbens leaves. The anti-inflammatory effects of n-hexane, ethanol, and aqueous extracts of G procumbens leaves were examined by BSA denaturation inhibitory activity. The anti-inflammatory activity of the aqueous extracts and reference (salicylic acid) was substantially distinct from that of the n-hexane and ethanol extracts. The significance level was specified as *P < 0.05, **P < 0.01, and ***P < 0.001 for aqueous extract versus salicylic acid (standard). The anti-inflammatory activity of the aqueous extract was substantially distinct from that of the ethanol and n-hexane extracts. The significance level was set at #P < 0.05, ##P < 0.01, and ###P < 0.001 for aqueous extract versus ethanol extract and $P < 0.05, $$P < 0.01, and $$$P < 0.001 for aqueous extract versus n-hexane extract. Values are presented as mean (SD) (n = 3 experiments).