Figure 2.

Cytotoxic effect of the aqueous extract of Gynura procumbens leaves on the heart, kidneys, and liver of experimental mice (Swiss albino) determined through histopathologic analysis. (A) Photograph of a heart segment from a normal mouse (fed with 5 g common dried rice for 4 weeks) exhibiting no deteriorating effect. (a₁) Photomicrograph of a heart segment from a mouse (fed with 5 g of the aqueous extract of G procumbens leaves for 4 weeks) exhibiting no deteriorating effect. (B) Photograph of the kidney segment from a normal mouse (fed with 5 g common dried rice for 4 weeks) exhibiting no deteriorating effect. (B₁) Photomicrograph of a kidney segment from a mouse (fed with 5 g aqueous extract of G procumbens leaves for 4 weeks) exhibiting no deteriorating effect. (C) Photograph of a liver segment from a control mouse (fed with 5 g normal dried rice for 4 weeks) exhibiting no deteriorating effect. (C₁) Photomicrograph of a liver segment from a mouse (fed with 5 g aqueous extract of G procumbens leaves for 4 weeks) exhibiting no deteriorating effect. Each value represents the mean (SEM) (n = 3 experiments). *Indicates significant differences between days 0 and 28 in the same treatment group at P < 0.05. **Indicates highly significant differences between days 0 and 28 in the same treatment group at P < 0.001.