Table 3.

Serum levels of TMAO before and after 4-week and 8-week treatment with Taurisolo® in study participants stratified for diagnosis of diabetes or hypertension.

	Baseline	t-4wk			t-8wk
	Mean ±SD	Mean ±SD	Δ% (vs. t0)	p (vs. t0)	Mean ±SD	Δ% (vs. t0)	p (vs. t0)
Diabetes (n = 28)	3.71 ± 2.81	2.11 ± 1.15	−43.15	<0.001	0.73 ± 0.67	−80.31	<0.0001
Hypertension (n = 39)	3.02 ± 2.87	1.79 ± 1.42	−40.84	0.0001	0.64 ± 0.64	−78.88	<0.0001
No-diabetes/No-hypertension (n = 41)	1.32 ± 1.10	0.66 ± 0.63	−49.82	<0.0001	0.40 ± 0.32	−69.92	<0.0001

Statistical significance was calculated with Student's t-test; p < 0.05 was considered as significant.