μCT assessment of the fusion mass at four weeks after implantation (a, b,
c Cross-section views, d–i 3D reconstructions). In the cross-section
view, more new bone formation was induced in the 18 rats implanted with
CBD-BMP2 + PRP (a) and the 18 rats with CBD-BMP2 (b) than the 17 rats
with PRP (c). The white arrow indicates implant site. In 3D
reconstructions images (d, e, f dorsal view, g, h, i ventral view),
continuous and considerable fusion mass was only observed in rats
implanted with CBD-BMP2 + PRP (d, g). In rats implanted with CBD-BMP2
(e, h), the fusion mass was relatively smaller than those with
CBD-BMP2 + PRP (d, g). In rats implanted with PRP (e, h), the new bone
formation was scattered, which was not merged into a whole mass. (A
color version of this figure is available in the online journal.)