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. 2021 Jul 19;12:708696. doi: 10.3389/fpsyg.2021.708696

Table 1.

Summary of articles included in the current literature review.

Author (year) and place Sample size and setting Design Duration and components Measurement tools Follow-up Main findings
Alkhawaldeh et al. (2020), Jordan Total (N = 184):
Treatment (n = 92);
Control (n = 92); CHCC
Cluster-RCT 2-week SMIP (six 2-hour sessions twice a day) Waitlist control group NSS Brief COPE Scale Baseline, after the intervention and follow-up 2 months after the intervention ↓ stress after the intervention and at follow-up (p =0.001) ↑ coping strategies after intervention and at follow-up (p =0.001)
Bahmanzadeh and Haji Alizadeh (2017), Iran Total (N = 30):
Treatment (n = 15);
Control (n = 15); Hospital
Quasi-experimental, pretest-posttest study with control 8-week cognitive-behavioral training (75 min/week) Passive control group DASS WHOQOL-BREF Baseline and after the intervention ↓ stress and anxiety (p < 0.05) ↑ quality of life (p < 0.05)
Bernburg et al. (2019), Germany Total (N = 86):
Treatment (n = 44);
Control (n = 42); Psychiatric hospitals
Randomized controlled pilot study 12-week mental health program (1.5–2 h/week) Waitlist control group PSQ ERSQ-27 BRCS SWOP-K9 QRI Evaluation form Baseline and three follow-ups over a period of 36 weeks (after 3 months, T1; after 6 months, T2; after 12 months, T3) ↓ stress at T1 (p < 0.01), T2 (p < 0.01) and T3 (p < 0.01) ↑ for all additional outcomes at T1, T2and T3 (p < 0.05) ↑ program evaluation
Bernburg et al. (2020), Germany Total (N = 94):
Treatment (n = 47);
Control (n = 47); Hospital
RCT 12-week work-related self-care skill training (1.5 h/week) Waitlist control group PSQ COPSOQ MBI-EE ERSQ-27 Evaluation form Baseline and three follow-ups over a period of 36 weeks (after 3 months, T1; after 6 months, T2; after 12 months, T3) ↓ stress at T1 (p < 0.001), T2 (p < 0.001) and T3 (p < 0.01) ↑ emotional exhaustion and emotion regulation skills at T1, T2and T3 (p < 0.05) ↑ job satisfaction at T1 (p = 0.01) ↑ program evaluation
Calder Calisi (2017), USA Total (N = 46):
Treatment (n =24);
Control (n =22); General Hospital
Randomized, waitlist control design 8-week RR (45-min session; self-practice 10-20 min twice a day) Waitlist control group STAI Semantic differential scales Baseline and after the intervention ↓ anxiety (p = 0.02) and stress (p = 0.003) ↑ confidence in teaching RR (p < 0.001)
Cohen-Katz et al. (2005), USA Total (N = 27):
Treatment (n = 14);
Control (n = 13); Academic-community—based Hospital
Pretest-posttest control group design with randomization 8-week MBSR program (2.5 h/week; home-based practice 6 days/week) Waitlist control group MBI BSI MAAS Evaluation form Baseline (T1), after the intervention (T2) and 3-month follow-up (T3) ↓ emotional exhaustion (MBI) at T2 and T3 (p < 0.05) ↑ MAAS at T2 (p = 0.004) and T3 (p = 0.002) ↑ program evaluation
Collier et al. (2018), USA and UK Total (N = 16):
Treatment (n = 8);
Control (n = 8); Psychiatric inpatient unit (Hospital and Mental Health Services)
Randomized trial 4-week MSET (two 40-min sessions/week) Control group; standard unit lounge Pulse rate STAI POMS Evaluation form Before and after each session ↓ pulse rate (p = 0.001), in State scale (p < 0.001) and Trait scale (p = 0.015) ↑ Confusion Bewilderment sub-scale of POMS (p = 0.004) ↑ program evaluation
Ghawadra et al. (2020), Malaysia Total (N = 249:
Treatment (n = 123);
Control (n = 126); Teaching hospital
RCT 4-week mindfulness-based intervention (2-hour workshop; self-practice guided by a website) Waitlist control group DASS-21 JSS MAAS Baseline, after the intervention and follow-up 8 weeks after the intervention ↓ stress (p < 0.001), anxiety (p = 0.001) and depression (p < 0.001) over time ↑ mindfulness (p < 0.001) over time ↑ job satisfaction (p < 0.001)
Gollwitzer et al. (2018), Germany Total (N = 129):
Treatment (MCII, n = 41; IIMCII, n = 41);
Control (n = 47); Health institutions
Randomized factorial design 3-week MCII (mental exercise daily) 3-week IIMCII (modified mental exercise daily) Passive control group PSQ-20 Physical symptoms subscale of BOSS II UWES-9 Baseline and after the intervention ↓ stress in the MCII group compared to the control group (p = 0.019) ↑ work engagement in the MCII group as compared to the IIMCII (p = 0.029) and the control group (p = 0.046)
Hersch et al. (2016), USA Total (N = 104):
Treatment (n = 52);
Control (n = 52); Hospital
RCT 12-week web-based BREATHE program (unlimited online access) Waitlist control group NSS Symptoms of Distress Coping with Stress WLQ Use of Substances for Stress Relief Drinking Quantity and Frequency Understanding Depression and Anxiety Nurses Job Satisfaction Scale Baseline and after the intervention ↓ stress (p < 0.001) and NSS sub-scales (p < 0.05) apart from sub-scale lack of support No effect on additional outcomes
Hsieh et al. (2020), Taiwan Total (N = 135):
Treatment (BT, n = 49; SDBT, n = 47) Control (n = 39); Psychiatric wards
Quasi-experimental study 6-week BT (1 h/week) 6-week SDBT (once a week) Waitlist control group CES-D OSI-2 RS Physiological parameters (HRV: SDNN, LF, HF; RR) Rehabilitation strength chart Simplified health scale Baseline and after the intervention ↓ stress (p =0.013) in SDBT group ↑ depressive symptoms (p < 0.001), resilience (p < 0.001), and respiration rate for BT (p < 0.001) and SDBT (p = 0.002)
Hwang and Jo (2019), Korea Total (N = 60):
Treatment (n = 30);
Control (n = 30); College hospital
RCT 4-week app-based stress-management program (twice a week for at least 10 min) Waitlist control group PSSKOSS(PHQ)-9(GAD)-7Korean-Emotional Labor scaleWHO-5 Well-Being IndexSelf-efficacy (Likert) scaleEvaluation form Baseline and after the intervention ↓ stress (PSS, p = 0.035; KOSS, p = 0.04) and emotional labor (p = 0.027)↑ well-being (p = 0.005) and self-efficacy (p = 0.025)↑ program evaluation
Kurebayashi et al. (2012), Brazil Total (N = 75):
Treatment (Needle group, n = 27; Seed group, n = 26);
Control (n = 22); Teaching hospital
RCT 8-week auriculotherapy with needles (eight sessions, 5-10 min/week) 8-week auriculotherapy with seeds (eight sessions, 5-10 min/week) Passive control group LSS Folkman and Lazarus' Ways of Coping questionnaire Baseline, after 4 sessions, after 8 sessions and follow-up 15 days after the intervention ↓ stress after 8 sessions (p = 0.020) and at follow-up (p = 0.003) in the needle group ↑ Distancing domain (p = 0.039) and Confrontive Coping domain (p = 0.029) at follow-up in the needle group ↑ Seeking Social Support domain (p = 0.022) after 8 sessions in the seed group
Lary et al. (2019), Iran Total (N = 70):
Treatment (n = 35);
Control (n = 35); Teaching hospital
Quasi-experimental study 6-week McNamara educational method (1 h/week) Waitlist Control group SRI Baseline, after the intervention and follow-up 8 weeks after the intervention ↓ stress (p = 0.021) over time
Lin et al. (2019), China Total (N = 90):
Treatment (n = 44);
Control (n = 46); General hospital
Randomized controlled design Modified 8-week MBSR program (group sessions 2 h/week and home-based practice 20 min × 6 days/week) Waitlist control group PSS PANAS CD-RISC MMSS Baseline, after the intervention (T1), and follow-up 3 months later (T2) ↓ stress and negative affect at T1 (p < 0.01) and T2 (p < 0.05) respectively ↑ positive affect at T1 and T2 (p < 0.05) and resilience at T2 (p < 0.05) No effect on job satisfaction
McElligott et al. (2003), USA Total (N = 20):
Treatment (n = 12);
Control (n = 8); University Hospital
Quasi-experimental design 4-week AMMA therapy (1 h/week) Control group; 4-week STTP Physiologic Parameters (blood pressure, heart rate, pulse oximetry, and skin temperature) VAS Evaluation interview questionnaires Baseline, before and after each treatment, and at completion of the study ↓ anxiety over time No effect on physiologic parameters ↑ program evaluation
Moeini et al. (2011), Iran Total (N = 58):
Treatment (n = 29);
Control (n = 29); Training hospital
Quasi-experimental study 3-week cognitive-behavioral program based on PRECEDE model (five 60-90 min sessions) Passive control group NSS Questionnaire based on PRECEDE model Evaluation form Baseline and follow-up 1.5 months after the intervention ↓ stress (p < 0.001) ↑ PRECEDE model constructs and stress management behaviors (p < 0.001)
Nazari et al. (2015), Iran Total (N = 66):
Treatment (n = 33);
Control (n = 33); ICUs (Hospital)
RCT 4-week massage therapy (25-min sessions twice a week) Passive control group OSI Baseline, after the intervention and follow-up 2 weeks after the intervention ↓ stress (p < 0.001) and subscale scores (p < 0.05) over time
Niva et al. (2020), India Total (N = 30):
Treatment (n = 15);
Control (n = 15); Tertiary care hospital
RCT Mahamantra chanting intervention for 45 days (20 min/day) Passive control group Stress biomarkers (Serum cortisol, DHEA-S, SAA) Biochemical parameters (Glucose and lipid profile) Baseline and follow-up after 2 menstrual cycles after the intervention ↓ serum cortisol (p = 0.012), SAA level (p = 0.04), glucose (p = 0.001), HbA1c (p = 0.041), total cholesterol (p < 0.001), LDLc (p < 0.001) and TGL (p = 0.17) ↑ HDLc (p = 0.033)
Orly et al. (2012), Israel Total (N = 36):
Treatment (n = 20);
Control (n = 16); Hospital
Pre-posttest design study with control 16-week CBI course (4 h/week) and five job-related 3-hour seminars Control group; five job-related 3-hour seminars SOC PSS POMS Baseline and after the intervention ↓ stress (p < 0.05) and POMS fatigue (p < 0.05) ↑ SOC (p < 0.05) and POMS vigor (p < 0.05)
Palumbo et al. (2012), USA Total (N = 14):
Treatment (n = 7);
Control (n = 7); Hospital
RCT 15-week Tai Chi program (group practice 45 min/week and self-practice at least 10 min × 4 days /week) Passive control group SF-36 Health Survey NSS PSS Sit-and-reach test Isometric knee extensor strength test dynamometer Functional reach test Nordic Musculoskeletal Questionnaire WLQ Work absenteeism Baseline and after the intervention No effect on stress ↑ work productivity (p = 0.03) and functional reach (p < 0.01)
Prado et al. (2018), Brazil Total (N = 168):
Treatment (Auriculotherapy, n = 56; Placebo, n = 56);
Control (n = 56); Hospital
Randomized, single-blind, controlled trial Auriculotherapy with stress points (12 sessions, twice a week) Sham auriculotherapy with sham points (12 sessions, twice a week) Waitlist control group LSS Baseline, after eight sessions, 12 sessions and follow-up 15 days after the end of the applications ↓ stress in the treatment group after eight sessions and at follow-up (p < 0.001) ↓stress in the placebo group after 12 sessions (p < 0.001) and at follow-up (p < 0.05)
Singh and Jain (2017), India Total (N = 40):
Treatment (n = 20);
Control (n = 20); Hospital
Pre-posttest design with control Self-help intervention (four 30-min sessions with an interval of 10 days) Passive control group Psychosocial Stress Questionnaire Occupational Stress Index Baseline and after the intervention ↓ occupational stress and in psychosocial stress (p < 0.01)
Villani et al. (2013), Italy Total (N = 30):
Treatment (n = 15);
Control (n = 15); Oncology hospital
Between-subjects design 4-week M-SIT (15-min sessions twice a week) Control group; neutral stimuli (15-min sessions twice a week) MSP STAI COPE-4 JCQ Baseline, before and after each session, after the intervention ↑ state anxiety (p < 0.001), trait anxiety (p = 0.041) and coping skills acquisition (p < 0.05)
Walker (2006), USA Total (N = 98):
Treatment (n = 58);
Control (n = 40); Hospital
Quasi-experimental design 4-week HRTT HeartTouch technique (3-hour educational session; self-practice; 1-hour session 2 weeks after the initial session; final follow-up session) Control group (2-hour educational session; final follow-up session) PSS SWB DRS Diary HeartTouch questionnaire Baseline and after the intervention ↓ stress (p < 0.001), and ↑ hardiness (p < 0.001) and spiritual well-being (p < 0.05) in the treatment group ↓ stress (p < 0.001) and ↑ hardiness (p < 0.05) in the control group
Wang et al. (2017), Taiwan Total (N = 78):
Treatment (MBSR, n = 35; Humanities class, n = 35);
Control (n = 12); Hospital
Quasi-experimental design 8-week MBSR intervention (3 h/week) 8-week humanities class (3 h/week) Passive control group FFMQ NSC Baseline (T0), after 1st month of MBSR (T1), after the intervention (T2), at 3rd month (T3) and 6th month (T4) ↑ mindfulness (p = 0.031) in the MBSR group
Yang et al. (2018), China Total (N = 100):
Treatment (n = 50);
Control (n = 50); Psychiatric departments
Pre-posttest design with control 8-week MBSR therapy (once a week; either group training or home-based practice) Control group; routine psychological support SCL-90 SDS SAS NSS Baseline and after the intervention ↓ stress, anxiety and depression scores (p < 0.001) ↑ mental health (p < 0.001)

↓ decrease, ↑ improvement or positive. AMMA therapy, a healing art of therapeutic massage; BOSS II, Burnout Screening Scales II inventory; Brief COPE Scale, Brief Coping Orientations for Experienced Problems Scale; BRCS, Brief Resilient Coping Scale; BREATHE, Stress Management for Nurses program; BSI, Brief Symptom Inventory; BT, biofeedback training; CBI, cognitive-behavioral intervention; CD-RISC, Connor–Davidson Resilience Scale; CES-D, Center for Epidemiological Studies Depression; CHCC, Comprehensive Health Care Centers; COPE, Brief Coping Orientation to Problems Experienced questionnaire; COPSOQ, Copenhagen Psychosocial Questionnaire; DASS, Depression, Anxiety and Stress Scale; DHEA-S, sulphated metabolite of dehydroxyepiandrosterone; DRS, Dispositional Resilience Scale; ERSQ-27, Emotion Regulation Skills Questionnaire; FFMQ, five facet mindfulness questionnaire; GAD-7, Generalized Anxiety Disorder; HbA1c, glycated hemoglobin; HDLc, high density lipoprotein cholesterol; HF, high frequency; HRTT, HeartTouch technique; HRV, heart rate variability; IIMCII, modified strategy of MCII; JCQ, Job Content Questionnaire; JSS, Job Satisfaction Scale for Nurses; KOSS, Korean Occupational Stress Scale; LDLc, low density lipoprotein cholesterol; LF, low frequency; LSS, Stress Symptom List; MAAS, Mindfulness Attention Awareness Scale; MBI-EE, emotional exhaustion subscale of the Maslach Burnout Inventory; MBSR, mindfulness-based stress reduction; MCII, mental contrasting with implementation intentions; MMSS, McCloskey/Mueller satisfaction scale; MSET, multisensory environmental therapy; M-SIT, Mobile Stress Inoculation Training; MSP, Mesure du Stress Psychologique; NSC, nurse stress checklist; NSS, Nursing Stress Scale; OSI, Occupational Stress Inventory; OSI-2, Occupational Stress Indicator; PANAS, positive and negative affect schedule; PHNs, public health nurses; PHQ-9, Patient Health Questionnaire; POMS, Profile of Mood States; PRECEDE, predisposing, reinforcing and enabling factors; PSQ, Perceived Stress Questionnaire; PSQ-20, Perceived Stress Questionnaire-20; PSS, Perceived Stress Scale; QRI, German Quality of Relationship Inventory; RCT, Randomized controlled trial; RR, Relaxation Response; RR, respiration rate; RS, Resilience Scale; SAA, salivary alpha amylase; SAD, stress, anxiety or depression; SAS, Self-rating anxiety scale; SCL-90, Symptom Checklist-90; SDBT, smartphone-delivered biofeedback training; SDNN, standard deviation of normal to normal; SDS, Self-rating depression scale; SMIP, stress management interventional program; SOC, Sense of Coherence; SRI, Stress Response Inventory; STAI, State Trait Anxiety Inventory; STTP, Standardized Touch Therapy Protocol; SWB, Spiritual Well-Being Scale; SWOP-K9, Self-Efficacy, Optimism and Pessimism questionnaire; TGL, triglycerides; UWES-9, Utrecht Work Engagement Scale; VAS, Visual Analog Scale; WHOQOL-BREF, World Health Organization Quality-of-Life Scale; WLQ, Work Limitations Questionnaire.