Table 3.
ELF Index Performance for Identification of Liver Fibrosis/Cirrhosis in HIV/HCV Versus HCV Patients
| HIV/HCV | HCV | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| ELF Index Cutoff | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | ELF Index Cutoff | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | |
| Any/mild fibrosis ≥F1 | 7.42 | 100 | 12 | 85 | 100 | 7.91 | 100 | 11 | 83 | 100 |
| 7.86 | 98 | 24 | 86 | 67 | 8.3 | 99 | 39 | 88 | 88 | |
| 8.45 | 85 | 60 | 91 | 46 | 8.72 | 85 | 67 | 92 | 50 | |
| 8.52 | 81 | 68 | 93 | 43 | 8.85 | 81 | 89 | 97 | 52 | |
| 8.85 | 68 | 84 | 95 | 35 | 8.91 | 76 | 89 | 97 | 46 | |
| 8.89 | 66 | 88 | 96 | 34 | 9.05 | 67 | 100 | 100 | 41 | |
| 9.09 | 56 | 100 | 100 | 32 | … | … | … | … | … | |
| Advanced fibrosis ≥F3 | 9.48 | 97 | 89 | 74 | 99 | 9.49 | 100 | 90 | 81 | 100 |
| 9.62 | 89 | 96 | 86 | 96 | 9.62 | 97 | 94 | 88 | 98 | |
| 9.81 | 71 | 98 | 93 | 92 | 9.8 | 73 | 99 | 96 | 89 | |
| Cirrhosis F4 | 9.49 | 100 | 79 | 37 | 100 | 9.69 | 100 | 82 | 48 | 100 |
| 9.81 | 81 | 89 | 48 | 98 | 9.8 | 93 | 88 | 57 | 99 | |
| 10.18 | 69 | 98 | 79 | 96 | 10.17 | 71 | 98 | 83 | 95 | |
| 10.45 | 63 | 99 | 80 | 94 | 10.41 | 64 | 99 | 90 | 94 | |
| 11.34 | 38 | 100 | 100 | 93 | 11.14 | 7 | 100 | 100 | 87 |
Abbreviations: ELF, enhanced liver fibrosis; HCV, hepatitis C virus; HIV, human immunodeficiency virus; NPV: negative predictive value; PPV, positive predictive value.