Table 5.

ELF Index, FIB4, and APRI Performance in HIV/HCV Versus HCV Infection

	Variable	HIV/HCV						HCV
		n = 147			P			n = 98			P
		ELF Index	FIB4	APRI	ELF ~ FIB4	ELF ~ APRI	FIB4 ~ APRI	ELF Index	FIB4	APRI	ELF ~ FIB4	ELF ~ APRI	FIB4 ~ APRI
Any/mild fibrosis ≥F1	AUC	0.82	0.72	0.74	.162	.327	.557	0.91	0.73	0.71	.000	.001	.110
	SEa	0.04	0.06	0.06				0.033	0.056	0.06
	95% CIb	.74–.89	.63–.79	.65–.82				.83–.96	.63–.82	.60 –.80
Advanced fibrosis ≥F3	AUC	0.97	0.71	0.599	<.000	<.000	.008	0.98	0.83	0.84	.001	.002	.074
	SEa	0.016	0.056	0.063				0.010	0.049	0.048
	95% CIb	.92–.99	.62–.79	.51– .69				.93–.100	.73–.90	.75–.91
Cirrhosis F4	AUC	0.98	0.83	0.79	.014	.0125	.216	0.99	0.94	0.90	.62	.55	.23
	SEa	0.015	0.073	0.085				0.011	0.025	0.046
	95% CIb	.94– .100	.75–.89	.71–.86				.93–.100	.87–.98	.82–.96

Abbreviations: APRI, aspartate to platelet ratio index; AUC, area under the curve; CI, confidence interval; ELF, enhanced liver fibrosis; HCV, hepatitis C virus; HIV, human immunodeficiency virus; SE, standard error.

^aDeLong et al 1988.

^bBinomial exact.