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. 2020 Dec 23;73(3):e629–e637. doi: 10.1093/cid/ciaa1879

Table 1.

Seroprevalence of Chlamydia trachomatis Overall and Stratified by Individual-Level Characteristics in US Females Ages 18-39, as Measured by 4 Definitions of Seropositivitya

ELISA MBA Both Either
Characteristics Weighted % (95% CI) Weighted % (95% CI) Weighted % (95% CI) Weighted % (95% CI)
Overall 30.0 (25.5–35.0) 29.4 (25.8–33.0) 23.0 (19.7–27.0) 36.3 (32.0–41.0)
Age, y
 18–24 27.4 (22.4–32.9) 27.9 (22.9–33.2) 21.7 (17.8–25.9) 33.6 (27.8–39.8)
 25–29 29.3 (23.3–35.8) 27.4 (22.6–32.6) 22.1 (17.3–27.4) 34.6 (28.8–40.8)
 30–34 31.5 (24.6–39.1) 30.4 (23.9–37.5) 21.3 (16.0–27.4) 40.6 (34.4–46.9)
 35–39 32.3 (25.3–40.0) 32.4 (25.2–40.3) 27.5 (21.2–34.5) 37.3 (29.1–45.9)
Race/ethnicity
 Non-Hispanic White 23.0 (18.1–28.5) 21.4 (17.5–25.7) 14.8 (11.6–18.5) 29.6 (24.9–34.6)
 Non-Hispanic Black 60.5 (54.4–66.5) 68.0 (61.1–74.5) 59.7 (53.5–65.8) 68.8 (61.9–75.2)
 Mexican American 31.8 (25.9–38.2) 30.9 (26.1–36.0) 25.4 (20.6–30.7) 37.4 (31.5–43.5)
 Other Hispanic 35.1 (27.8–42.9) 35.0 (28.1–42.4) 28.7 (21.8–36.6) 41.3 (34.7–48.2)
 Non-Hispanic Asian 17.0 (11.0–24.4) 15.5 (10.3–22.1) 9.9 (5.6–15.8) 22.6 (16.1–30.2)
 Other race, including multiracial 43.0 (23.2–64.5)a 35.9 (22.5–51.2) 33.4 (21.2–47.6) 45.5 (24.2–68.1)a
Born in the 50 US states
 No 30.3 (25.3–35.7) 29.8 (25.5–34.5) 23.5 (19.7–27.6) 36.7 (31.6–42.0)
 Yes 28.5 (23.0–34.4) 27.4 (23.4–31.7) 21.0 (16.7–26.0) 34.8 (29.7–40.2)
Poverty status
 Below the poverty level 39.2 (33.0–45.6) 42.4 (35.8–49.2) 35.1 (29.6–41.0) 46.4 (39.5–53.4)
 At or above poverty level 26.3 (21.7–31.4) 25.0 (21.0–29.3) 19.0 (15.6–22.7) 32.4 (27.8–37.2)
Education
 Less than high school 36.8 (30.2–43.8) 41.6 (34.7–48.7) 32.2 (26.0–38.9) 46.2 (38.9–53.6)
 GED/high school degree/some college 34.0 (27.2–41.2) 34.5 (27.5–42.1) 28.2 (21.9–35.2) 40.3 (33.2–47.8)
 College degree of higher 27.4 (22.6–32.5) 25.4 (22.0–29.0) 19.6 (16.7–22.8) 33.1 (28.5–38.1)
Marital status
 Never married 34.7 (29.5–40.3) 33.9 (29.1–38.8) 29.2 (25.1–33.6) 39.4 (33.7–45.3)
 Married/living with partner 25.8 (21.3–30.6) 26.2 (21.7–31.1) 18.6 (15.0–22.7) 33.3 (28.7–38.1)
 Widowed/divorced/separated 48.6 (35.2–62.2) 45.7 (35.5–56.1) 38.2 (28.6–48.6) 56.1 (42.9–68.6)
 Not askedb 23.4 (15.9–32.4) 18.9 (12.4–26.8) 15.3 (10.7–20.8) 27.0 (18.5–37.0)
Lifetime sexual partners
 0–1 11.2 (7.0–16.8) 7.4 (4.9–10.7) 4.8 (3.0–7.1) 13.9 (9.1–20.0)
 2–3 23.9 (17.3–31.4) 18.6 (13.4–24.9) 14.3 (10.3–19.1) 28.2 (21.0–36.4)
 4–7 37.1 (30.4–44.3) 40.7 (33.7–48.0) 33.1 (27.3–39.4) 44.7 (37.0–52.6)
 8–15 37.4 (28.8–46.7) 38.5 (31.7–45.8) 29.8 (23.0–37.3) 46.2 (37.8–54.7)
 > 15 43.2 (31.0–56.0) 47.2 (36.9–57.6) 38 (27.9–48.9) 52.3 (40.3–64.2)
Sexual partner over past 12 mo
 0 18.6 (10.0–30.3) 14.5 (8.8–21.9) 9.6 (4.9–16.3) 23.5 (14.3–34.9)
 1 28.1 (23.8–32.8) 27.8 (23.9–32.0) 22.1 (18.8–25.7) 33.8 (29.2–38.8)
 2 38.7 (30.4–47.5) 40.2 (34.0–46.7) 31.4 (25.0–38.3) 47.5 (39.9–55.2)
New sexual partner over past 12 mo
 No 28.1 (23.6 – 33.0) 27.7 (23.8–31.8) 21.9 (18.6–25.4) 33.9 (29.0–39.0)
 Yes 34.9 (27.4 – 43.0) 34.9 (28.5–41.7) 26.8 (20.8–33.6) 43.0 (36.0–50.2)
Age of sexual debut, yc
 ≤16 42.1 (36.9–47.4) 43.4 (38.7–48.2) 35.5 (31.6–39.6) 49.9 (44.1–55.7)
 17–18 24.8 (17.6–33.3) 26.5 (21.7–31.8) 19.0 (14.2–24.6) 32.4 (25.3–40.1)
 ≥19 13.6 (9.1–19.2) 10.2 (6.3–15.3) 7.3 (4.7–10.6) 16.5 (12.0–22.0)

All data are weighted using pooled Medical Examination Center (MEC) survey weights provided by the National Center for Health Statistics.

Abbreviations: CI, confidence interval; ELISA, enzyme-linked immunosorbent assay; IgG, immunoglobin G; MBA, multiplex bead format assay; US, United States.

aDefinitions of positivity: ELISA, positive on the anti-pgp3 ELISA; MBA, positive on the anti-pgp3 MBA; both, positive on both an anti-pgp3 MBA and ELISA; either, positive on either the anti-pgp3 MBA and ELISA.

bNot asked of participants ages 18 to 19 years.

cOnly among those sexually experienced.