Table 2.
Distribution of Composite Mother–Fetus/Infant Paired Outcomes in the TB APPRISE Study
| Maternal–Fetus/Infant Category | Composite Outcome Score | Composite Outcome Average Ranka | Composite Outcome Rank | Frequency (%) | Cumulative Frequencyb (%) | ||
|---|---|---|---|---|---|---|---|
| Immediate INH (n = 460) | Deferred INH (n = 466) | Immediate INH (n = 460) | Deferred INH (n = 466) | ||||
| A | 100 | 921.5 | 8 | 3 (0.7) | 7 (1.5) | 460 (100.0) | 466 (100.0) |
| B | 90 | 904.0 | 7 | 10 (2.2) | 15 (3.2) | 457 (99.3) | 459 (98.5) |
| C | 80 | 843.0 | 6 | 60 (13.0) | 37 (7.9) | 447 (97.2) | 444 (95.3) |
| D | 75 | … | 5 | 0 (0.0) | 0 (0.0) | 387 (84.1) | 407 (87.3) |
| E | 70 | 758.5 | 4 | 34 (7.4) | 38 (8.2) | 387 (84.1) | 407 (87.3) |
| F | 65 | 686.0 | 3 | 40 (8.7) | 33 (7.1) | 353 (76.7) | 369 (79.2) |
| G | 60 | 495.5 | 2 | 152 (33.0) | 156 (33.5) | 313 (68.0) | 336 (72.1) |
| H (no event) | 0 | 171.0 | 1 | 161 (35.0) | 180 (38.6) | 161 (35.0) | 180 (38.6) |
| Score: mean (SD) | … | … | … | 43.7 (33.0) | 41.2 (33.7) | … | … |
Abbreviation: APPRISE, Ante vs. Postpartum Prevention with INH in HIV Seropositive mothers and their Exposed infants; INH, isoniazid; SD, standard deviation; TB, tuberculosis.
aAverage rank for mother–infant pairs in the trial data with the same score.
bProportion less than or equal to score.