Table 2.

Body Mass Index (BMI) Change Over Time in the Full Cohort and Stratified by BMI Category

Rate of BMI Increase Before and After DTG	Full Cohort (N = 460)	Thin (n = 40)	Normal (n = 393)	Obese/Overweight (n = 27)
Before	0.3 (.2–.4)***	0.3 (.1–.5)*	0.3 (.2–.4)***	0.5 (.0 to 1.1)
After	1.2 (1.1–1.3)***	1.0 (.7–1.2)***	1.2 (1.1–1.3)***	1.2 (.5–1.9)**
Difference	0.8 (.7–1.0)***	0.7 (.3–1.1)***	0.9 (.7–1.0)***	0.7 (–.5 to 1.8)

Data are presented as kg/m² per year (95% confidence interval). Selected coefficients relating to time on or off DTG are shown after adjusting for age at DTG transition, previous medications, DTG companion drugs, and sex.

Abbreviations: BMI, body mass index; DTG, dolutegravir.

*P < .05; **P < .01; ***P < .001.