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. 2021 Jul 19;15:698007. doi: 10.3389/fnins.2021.698007

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Copyright © 2021 de Planque, Mutsaerts, Keil, Erler, Dremmen, Mathijssen and Petr.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A single axial slice is shown (columns left to right) for the T1-weighted image and the ASL image in their native space before registration and for the results of the four registration methods in the standard space: regT1, regASLrigid, regASLaffine, and regASLdct of three trigonocephaly subjects (rows). In the standard space, a CBF image is shown with borders of the WM from the template (with a threshold at 50%) shown in red. Finally, the pseudo-CBF images of the three trigonocephaly patients are shown.