Table 1.
Participant Characteristics at Baseline
| Total | Treated | Placebo | ||||
|---|---|---|---|---|---|---|
| Females (N = 214) | Males (N = 214) | Females (n = 107) | Males (n = 107) | Females (n = 107) | Males (n = 107) | |
| Age, mean (SD), years | 32.1 (7.5) | 34.3 (9.6) | 31.5 (6.9) | 33.9 (9.5) | 32.8 (8.1) | 34.8 (9.7) |
| Race, n (%) | ||||||
| Black or African American | 177 (83) | 181 (85) | 89 (83) | 93 (87) | 88 (82) | 88 (83) |
| White | 29 (14) | 21 (10) | 14 (13) | 9 (8) | 15 (14) | 12 (11) |
| Other/multiracial | 8 (4) | 11 (5) | 4 (4) | 5 (5) | 4 (4) | 6 (6) |
| Hispanic ethnicity, n (%) | 10 (5) | 5 (2) | 6 (6) | 3 (3) | 4 (4) | 2 (2) |
| Total partners, last 3 months, n (%) | ||||||
| ≥2 | 31 (14) | 39 (18) | 13 (12) | 19 (18) | 18 (17) | 20 (19) |
| 0–1a | 183 (86) | 175 (82) | 94 (88) | 88 (82) | 89 (83) | 87 (81) |
| Total partners, lifetime, n (%) | ||||||
| ≥11 | 60 (28) | 117 (55) | 30 (28) | 56 (52) | 30 (28) | 61 (57) |
| 6–10 | 77 (36) | 59 (28) | 46 (43) | 32 (30) | 31 (29) | 27 (25) |
| 1–5 | 76 (36) | 38 (18) | 30 (28) | 19 (18) | 46 (43) | 19 (18) |
| One or more new partners, last 3 months, n (%) | 13 (6) | 10 (5) | 6 (6) | 2 (2) | 7 (7) | 8 (7) |
| How often used a condom, last 3 months, n (%) | ||||||
| Always | 9 (4) | 8 (4) | 4 (4) | 3 (3) | 5 (5) | 5 (5) |
| Sometimes/never/don’t know | 204 (96) | 206 (96) | 103 (96) | 104 (97) | 101 (95) | 102 (95) |
| Used a condom at last sexual encounter, n (%) | 21 (10) | 23 (11) | 12 (11) | 13 (12) | 9 (8) | 10 (9) |
| Baseline STI-positive result, n (%) | ||||||
| Gonorrhea | 5 (2) | 0 (0) | 0 (0) | 0 (0) | 5 (5) | 0 (0) |
| Chlamydia | 6 (3) | 0 (0) | 0 (0) | 0 (0) | 6 (6) | 0 (0) |
| Lifetime STI history, n (%) | ||||||
| Any STI | 146 (68) | 107 (50) | 75 (70) | 58 (54) | 71 (66) | 49 (46) |
| Gonorrhea | 58 (27) | 55 (26) | 31 (29) | 28 (26) | 27 (25) | 27 (25) |
| Chlamydia | 93 (43) | 59 (28) | 45 (42) | 33 (31 | 48 (45) | 26 (24) |
| MPC | 2 (1) | … | 1 (1) | … | 1 (1) | … |
| NGU | … | 3 (1) | … | 1 (1) | … | 2 (2) |
| Trichomonas | 82 (38) | 20 (9) | 43 (40) | 10 (9) | 39 (36) | 10 (9) |
| Syphilis | 4 (2) | 2 (1) | 1 (1) | 1 (1) | 3 (3) | 1 (1) |
| Genital warts | 8 (4) | 4 (2) | 4 (4) | 2 (2) | 4 (4) | 2 (2) |
| Herpes | 14 (7) | 14 (7) | 7 (7) | 7 (7) | 7 (7) | 7 (7) |
Abbreviations: MPC, mucopurulent cervicitis; NGU, nongonococcal urethritis; SD, standard deviation; STI, sexually transmitted infection.
aOnly 1 male partner in each arm reported 0 sexual partners in the last 3 months.