Figure 2.

Roles of ZBTB proteins in the proliferation, differentiation and function of conventional T cells in the periphery. (A), a schematic view showing that ZBTB proteins regulate the survival, proliferation and/or function of undifferentiated CD4⁺ T cells, differentiated effector Th subsets, or Tm cells. (B), a schematic view illustrating roles of ZBTB proteins in CD8⁺ T cells along their differentiation into Te and final Tm process. ZBTB proteins with the superscript ‘m’, ‘h’ or ‘m/h’ in the upper right corner indicate that these proteins are ascribed to mice, humans or both, respectively.