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. 2021 Jul 19;12:707344. doi: 10.3389/fphys.2021.707344

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Copyright © 2021 Zou, Zhou, Xi, Huang and Hu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pioglitazone up-regulates PPAR-γ mRNA and protein expression. (A) Quantitative analysis of PPAR-γ mRNA in the kidneys at 24 h post renal IRI. (B) Representative western blots indicating PPAR-γ protein level in the kidneys at 24 h after renal IRI. (C) Quantitative analysis of PPAR-γ protein level in the kidneys. Values are expressed as mean ± SE (n = 3). Compared to the sham group, ^∗ represents p < 0.05, and ^∗∗∗ represents p < 0.001; compared to the IRI group, ### represents p < 0.001; compared to the Pio + IRI group, + represents p < 0.05, and +++ represents p < 0.001.