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. 2021 Jul 19;12:707344. doi: 10.3389/fphys.2021.707344

FIGURE 6.

FIGURE 6

Pioglitazone decreases the mRNA expression of inflammation markers, including TNF-α and MCP-1, in the renal tissues at 24 h after renal IRI. (A,B) TNF-α and MCP-1 expression levels in the renal tissue of each group, respectively. Values are expressed as mean ± SE (n = 3). Compared to the sham group, ∗∗∗ represents p < 0.001; compared to the IRI group, ### represents p < 0.001; compared to the Pio + IRI group, +++ represents p < 0.001.