Table 4.
Distribution of Different HR-HPV Genotypes According to Cytological Diagnosis in Women with Pregnant or Non-Pregnant. (N=2154)
| Variate | Pregnant Women (n=1077) | Non-Pregnant Women (n=1077) | ||||
|---|---|---|---|---|---|---|
| NILM/ASC-US/LSIL (n=1064) | ≥HSILa (n=13) | P value | NILM/ASC-US/LSIL (n=1068) | ≥HSILa (n=9) | P value | |
| HPV | 23.5% (250) | 84.6% (11) | <0.001 | 14.2% (152) | 77.8% (7) | <0.001 |
| Single-type infectionb | 15.7% (167) | 53.8% (7) | <0.001 | 11.4% (121) | 44.4% (4) | 0.010 |
| Multi-type infectionsc | 7.8% (83) | 30.8% (4) | 0.012 | 3.0% (32) | 22.2% (2) | 0.030 |
| HR-HPV | 19.5% (207) | 84.6% (11) | <0.001 | 11.1% (119) | 77.8% (7) | <0.001 |
| HPV16 | 3.1% (33) | 38.5% (5) | <0.001 | 1.2% (12) | 22.2% (2) | 0.005 |
| HPV18 | 1.9% (20) | 7.7% (1) | 0.227 | 0.6% (5) | 11.1% (1) | 0.049 |
| HPV31 | 0.5% (5) | 7.7% (1) | 0.070 | 0.3% (3) | 22.2% (2) | 0.001 |
| HPV33 | 1.1% (12) | 7.7% (1) | 0.147 | 0.4% (4) | 11.1% (1) | 0.041 |
| HPV52 | 6.0% (64) | 7.7% (1) | 0.557 | 3.5% (37) | 22.2% (2) | 0.039 |
| HPV58 | 2.4% (26) | 15.4% (2) | 0.043 | 1.2% (12) | 22.2% (2) | 0.005 |
| Other Typesd | 9.4% (100) | 23.1% (3) | 0.233 | 6.4% (68) | 11.1% (1) | 0.450 |
Notes: aHigh grade squamous intraepithelial lesion or worse; bsuffer from a single human papillomavirus genotype infection; csuffer from at least two or more genotypes of human papillomavirus infection; dincluding types HPV-35, -39, -45, -51, -56, -59, -66, -68.
Abbreviations: HR-HPV, high-risk human papillomavirus, including types HPV-16, -18, -31, -33, -35, -39, -45, -51, -52, -56, -58, -59, -66, -68; NILM/ASC-US/LSIL, negative for intraepithelial lesion or malignancy/atypical squamous cells of undetermined significance/low-grade squamous intraepithelial lesions; ≥HSIL, high grade squamous intraepithelial lesion or worse.