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. 2021 Jul 19;12:699253. doi: 10.3389/fphys.2021.699253

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Copyright © 2021 Hartmann, Lang, Zeng, Duan, Zhang, Wang, Bondareva, Kruglov, Fouts, Stärkel and Schnabl.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Patients with alcohol use disorder (AUD) have a significantly different mycobiome from control subjects. (A) Principal coordinate analysis (PCoA) of mycobiome in AUD patients (n = 66) and controls (n = 18). (B,C) Linear discriminant analysis (LDA) of (B) genera and (C) species of AUD patients versus controls. (D–I) Relative abundance of genera (D) Candida, (E) Debaryomyces, (F) Issatchenkia, (G) Kluyveromyces, and of species (H) Candida albicans, and (I) Candida zeylanoides. A P value of equal or less than 0.05 was considered as statistically significant.