TABLE 2.
Proteins involved in transport activities.
| Protein family (gene name) | TCDB | Functional activity | Localization |
| Tweety family (TTYH1, TTYH2, TTYH3) | 1.A.48.-.- | Swelling-dependent volume-regulated anion channel in astrocytes | PM |
| OXA1/ALB3/YidC family (OXA1L, COX18) | 2.A.9.-.- | Insertases: translocation of COX2 and integral membrane proteins | Mitochondria IM |
| Sideroflexin family* (SFXN1, SFXN2, SFXN3, SFXN4, SFXN5) | 2.A.54.-.- | Amino acid transport | Mitochondria IM |
| TspO/BZRP family* (TSPO, TSPO2) | 9.A.24.-.- | Transmembrane signaling Mitochondrial respiration Cholesterol transport | ER, Vesicle, Vacuole Mitochondria OM |
| YIF1/YIP1 family* (YIF1A, YIF1B, YIPF1-7) | 9.B.135.-.- | COPII-coated ER to Golgi transport vesicle-mediated transport | Golgi apparatus, ER |
| CD47 | 1.N.1.-.- | Cell adhesion, membrane transport | PM, Vesicle |
| STIMATE | 8.A.65.-.- | Calcium channel regulator activity | ER, Vacuole |
| ARV1 | 9.A.19.-.- | Cholesterol transport | ER, Vesicle, |
| TMEM41A | 9.B.27.-.- | Putative transport protein; metastasis via modulation of E-cadherin | ER, Golgi apparatus |
Asterisk (*) indicates a family member is presumably involved in transport activity although it does not have an TCDB identifier associated with it. ER, endoplasmic reticulum; IM, inner membrane; OM, outer membrane; PM, plasma membrane; TCDB, Transporter Classification Database.