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. 2021 Jul 19;12:686133. doi: 10.3389/fphar.2021.686133

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Copyright © 2021 Li, Ning, Wei, Huang, Lu, Pang, Wu, Zhou, Zhou, Luo and Han.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PLS-DA and OPLS-DA analysis on plasma samples in placebo group. (A) PLS-DA analysis in positive mode. (B) Permutation test of PLS-DA analysis in positive mode. (C) PLS-DA analysis in negative mode. (D) Permutation test of PLS-DA analysis in negative mode. (E) OPLS-DA analysis in positive mode. (F) Permutation test of OPLS-DA analysis in positive mode. (G) OPLS-DA analysis in negative mode. (H) Permutation test of OPLS-DA analysis in negative mode. : T1 (Placebo), : T2 (Placebo), : T3 (Placebo), : T4 (Placebo).

Inline graphic — PLS-DA and OPLS-DA analysis on plasma samples in placebo group. (A) PLS-DA analysis in positive mode. (B) Permutation test of PLS-DA analysis in positive mode. (C) PLS-DA analysis in negative mode. (D) Permutation test of PLS-DA analysis in negative mode. (E) OPLS-DA analysis in positive mode. (F) Permutation test of OPLS-DA analysis in positive mode. (G) OPLS-DA analysis in negative mode. (H) Permutation test of OPLS-DA analysis in negative mode. : T1 (Placebo), : T2 (Placebo), : T3 (Placebo), : T4 (Placebo).