. Author manuscript; available in PMC: 2021 Aug 2.

Published in final edited form as: Urol Clin North Am. 2020 Jun 10;47(3):293–303. doi: 10.1016/j.ucl.2020.04.002

Table 1.

Prognostic models in advanced renal cell carcinoma

Prognostic Factors	MSKCC Motzer et al,¹¹ 2002	IMDC Heng et al,¹³ 2009	GFI Negrier et al,¹⁵ 2002	CCF Mekhail et al,¹² 2005	IKCWG Manola et al,¹⁶ 2011
Performance status	●	●	●		●
Elevated serum LDH	●			●	●
Low hemoglobin	●	●	●	●	●
High corrected serum Ca	●	●		●	●
Time from Dx to Tx <1 y	●	●	● ○	●	●
Prior radiotherapy				●
Number of metastatic sites			● ○	●	●
Hepatic metastasis			○
Elevated ANC		●	○		● (WBC)
Elevated platelets		●
Inflammation			●
Elevated ALP					●
Prior immunotherapy					●

Abbreviations: ●, prognostic factors for survival; ○, prognostic factors for rapid progression; ALP, alkaline phosphatase; ANC, absolute neutrophil count; Dx, diagnosis; GFI, Groupe Français d’Immunothérapie; Tx, therapy; WBC, white blood cells.